Class 2004 -Students
Students IGS-2004
Yen
Current Lab:
Molecular and Systemic
Neurobiology
Prof. Dr. Sigrun Korsching
Summary of my work:
Functional characterization of vomeronasal receptor neurons in
zebrafish
Olfaction is an intricate
network that involves two types of chemosensory channels in order to detect an array
of odours and pheromones. The main olfactory system is important for chemosensory
activation by volatile compounds whereas the vomeronasal system conveys
nonvolatile information to the higher brain. Vomeronasal receptor neuron is
suggested to be specialized for the detection of pheromones, biological
compounds that are secreted and have a defined physiological or behavioural
effect on an individual of the same species. There are two classes of vomeronasal receptor
genes namely, V1Rs (vomeronasal type-1 receptors) and V2R (vomeronasal type-2
receptors). V2Rs are express by the
microvillous olfactory sensory neurons and mediate the food behaviour. However,
to date, the information is scarce concerning the attribute of the VIRs’ neuron
and its function.
Hence, the aim of this study is to have a better understanding of the role play
by VIRs in olfactory system.
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